Located on the banks of the Manzanares River, Ermita de San Antonio de la Florida is a small church in neoclassical style , the work of the Italian architect Felipe Fontana, built between 1792 and 1798. Just in 1798 Francisco de Goya decorated its interior with a series of frescoes in which Episodes from the life of Saint Anthony of Padua are told, which constitute a masterpiece of the painter.

At the foot of the presbytery is Goya 's tomb. It is made of granite and has the attached limestone headstone that marked his grave in the cemetery of Bordeaux, the city where the artist died in 1828.

To ensure the conservation of his paintings, the Ermita de San Antonio de la Florida was declared a National Monument in 1905 and later, in 1928, an identical church was built next to it, to transfer the cult and reserve the original as a museum.